Botox is a household name now, but when the idea was proposed back in 1987 by Vancouver cosmetic surgeon Jean Carruthers, MD, she says the response from most women was “You want to inject what into my face?”

Dr. Carruthers told Prevention magazine that she “stumbled upon the anti-aging potential of botulinum toxin while conducting a study using it to prevent chronic eyelid spasms” when a patient mentioned the unexpected (and quite welcome) side effect of her forehead wrinkles vanishing.

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